Private Sub Form1_Load(ByVal sender As System.Object, ByVal e As _
      System.EventArgs) Handles MyBase.Load
        Me.KeyPreview = True
    End Sub
 
    Private Sub Form1_KeyDown(ByVal sender As Object, ByVal e As _
      System.Windows.Forms.KeyEventArgs) Handles MyBase.KeyDown
        If e.KeyCode = Keys.F5 Then
            '// deine routine
            Debug.WriteLine("f5 press")
        End If
    End Sub