Private Sub Button1_Click(ByVal sender As System.Object, ByVal e As _
      System.EventArgs) Handles Button1.Click
        '// Image laden
        Dim path As String = "C:\tmp\img.bmp"
        Me.PictureBox1.Image = Image.FromFile(path)
    End Sub
 
    Private Sub Button2_Click(ByVal sender As System.Object, ByVal e As _
      System.EventArgs) Handles Button2.Click
        '// Image freigeben
        Me.PictureBox1.Image.Dispose()
        Me.PictureBox1.Image = Nothing
    End Sub